Efficacy of radiotherapy in patients on progression after treatment with ipilimumab 3 mg/kg
نویسندگان
چکیده
منابع مشابه
The abscopal effect: efficacy of radiotherapy in patients on progression after treatment with ipilimumab 3 mg/kg
Background After more than 30 years, Ipilimumab was the first agent which showed a survival benefit for the treatment of metastatic melanoma. However, only about the 20% of patients have a long-term survival benefit. The combination of ipilimumab with other therapies might improve its efficacy. A new phenomenon also known as abscopal effect refers to a regression of metastatic lesions distant f...
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15 صفحه اولAutoimmune inflammatory myopathy after treatment with ipilimumab.
While human immunity is generally thought to protect against infectious agents, there is also evidence for immune surveillance against neoplastic diseases. Some malignant cells are able to evade or down-regulate this immune response through a variety of chemical mediators, rendering the host response ineffective and leading to poor prognoses. Immune mechanisms seem particularly important in the...
متن کاملRadiotherapy to Control Limited Melanoma Progression Following Ipilimumab
Durable local control of irradiated cancer and distant abscopal effects are presumably immune mediated. To evaluate the role of radiotherapy (RT) for limited progression after anti-CTLA4 checkpoint inhibition, medical records of all patients with surgically incurable stage III or IV melanoma from a single institution who received ipilimumab as first-line immunotherapy and subsequent RT were rev...
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ژورنال
عنوان ژورنال: Journal of Translational Medicine
سال: 2014
ISSN: 1479-5876
DOI: 10.1186/1479-5876-12-s1-o6